PRACTICAL VALUE OF LIVER FUNCTION TESTS

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Abstract
Although recent interest in liver function tests has been productive of much information and has developed many new methods, the hope that a single test would be found that could fulfil all requirements for adequately estimating liver function has thus far failed. No single test up to now can actually measure more than one specific function of the liver, whether metabolic, secretory or retentive. The large amount of work done in this field began with the contribution of Rowntree, Hurwitz and Bloomfield1in 1913, when they first called attention to the use of halogenated phthaleins as a means of testing the functions of the liver. Our studies were carried out over a period of four years on almost 300 patients referred to the gastro-enterologic clinic at the Hospital of the Graduate School of Medicine of the University of Pennsylvania. All the more important tests have been tried out at

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