Lack of Effect of Folic Acid on Scurvy in Guinea Pigs
- 1 March 1951
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 76 (3) , 574-576
- https://doi.org/10.3181/00379727-76-18562
Abstract
A relationship between ascorbic acid and folic acid has been indicated by the observation of the frequent association of scurvy with megaloblastic anemia in infants and the response of folic acid deficient rats to ascorbic acid. To determine the effect of folic acid on ascorbic acid deficiency, growing guinea pigs on a scorbutogenic diet were given folic acid subcut. A control group of animals was given normal saline. The cumulative mortality rates of the 2 groups were identical.Keywords
This publication has 3 references indexed in Scilit:
- AN IN VIVO EFFECT OF PTEROYLGLUTAMIC ACID UPON TYROSINE METABOLISM IN THE SCORBUTIC GUINEA PIGJournal of Biological Chemistry, 1948
- PHARMACOLOGICAL STUDIES OF PTEROYLGLUTAMIC ACIDAnnals of the New York Academy of Sciences, 1946
- MEGALOBLASTIC ANEMIA IN INFANCYAmerican Journal of Diseases of Children, 1946