Novel therapeutic strategies provide the real test for the amyloid hypothesis of Alzheimer's disease
- 1 July 2002
- journal article
- review article
- Published by Elsevier in Trends in Pharmacological Sciences
- Vol. 23 (7) , 324-330
- https://doi.org/10.1016/s0165-6147(02)02038-2
Abstract
No abstract availableKeywords
This publication has 75 references indexed in Scilit:
- An inflammatory drug prospectNature, 2001
- BACE knockout mice are healthy despite lacking the primary beta-secretase activity in brain: implications for Alzheimer's disease therapeuticsHuman Molecular Genetics, 2001
- Treatment with a Copper-Zinc Chelator Markedly and Rapidly Inhibits β-Amyloid Accumulation in Alzheimer's Disease Transgenic MicePublished by Elsevier ,2001
- Metabolic Regulation of Brain Aβ by NeprilysinScience, 2001
- Evidence for Genetic Linkage of Alzheimer's Disease to Chromosome 10qScience, 2000
- Structure of the Protease Domain of Memapsin 2 (β-Secretase) Complexed with InhibitorScience, 2000
- Aβ-Generating EnzymesNeuron, 2000
- Cyclo-Oxygenase-2 InhibitorsDrugs & Aging, 2000
- Aqueous Dissolution of Alzheimer's Disease Aβ Amyloid Deposits by Biometal DepletionJournal of Biological Chemistry, 1999
- Rapid induction of Alzheimer A beta amyloid formation by zincScience, 1994