UPTAKE OF TL-201 IN ENLARGED THYROID-GLANDS - CONCISE COMMUNICATION

  • 1 January 1979
    • journal article
    • research article
    • Vol. 20  (8) , 827-832
Abstract
The thyroid uptake of 201Tl was studied in 37 patients with various types of goiter, and in 6 with normal thyroids. Significant Tl uptake was found in all cases in which there was thyroid enlargement, including Graves'' disease, toxic thyroid nodule, primary hypothyroidism, simple goiter, Hashimoto''s disease, thyroid carcinoma and thyroid adenoma. If goiter was absent, however, there was no demonstrable uptake, e.g., in secondary hypothyroidism, subacute thyroiditis and the normal controls. Tl uptake did not correlate with thyroid function tests such as basal metabolic rate, triiodothyronine [T3] resin uptake, T3, thyroxine, thyrotropin, antithyroid antibodies or the 24 h 131I uptake. In 23 patients with diffuse goiter, maximum 201Tl uptake correlated well with thyroid weight: r [correlation coefficient] = 0.836 (P < 0.001); y = 0.02x + 0.06.

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