Exposure of simian virus‐40‐transformed human cells to magnetic fields results in increased levels of T‐antigen mRNA and protein

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Abstract
In its integrated form, SV‐40 DNA offers an opportunity to observe the behavior of what is in effect a viral genome within a cellular genome, with transcriptional and translational products that can be clearly distinguished from those of the host cell. Exposure of SV40‐transformed human fibroblasts to a 60 Hz continuous‐wave sinusoidal electromagnetic (EM) field resulted in increased levels of virally derived mRNA and protein of large T‐antigen. These findings provide evidence that a foreign DNA integrated into cells can be affected by EM fields under conditions known to cause increased transcripts from endogenous cellular genes.