Varicella Vaccine: Decisions a Little Nearer

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Abstract
The live attenuated varicella vaccines have generated much discussion. In the late 1970s, while the Japanese were testing their vaccine strains and publishing their results in American journals, the journal-reading pediatric community was treated to a veritable torrent of editorial and epistolary opinion on the merits and demerits of proceeding with clinical trials on home territory.1 2 3 4 There were many bothersome questions that surfaced in those printed pages. Was the vaccine needed in the first place? After all, zoster immune globulin could be used to prevent varicella in the highest risk group, and chickenpox in normal children was considered fairly benign. . . .

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