The ftsA Gene Product: a Possible Connection between DNA Replication and Septation in Escherichia coli
- 1 February 1985
- journal article
- research article
- Published by Microbiology Society in Microbiology
- Vol. 131 (2) , 239-244
- https://doi.org/10.1099/00221287-131-2-239
Abstract
The study of E. coli strain, D-2, which harbors the ftsA2(ts) allele, showed that temperature-induced filaments of this strain can divide at 30.degree. C in the absence of DNA replication and translation. Strain D-2 is thermosensitive during a period coincident with that in which the termination protein should be synthesized and exert its action. The ftsA gene product, which participates in the structure of the septum, needs for its synthesis a short period of DNA replication. The FtsA protein could be involved in a mechanism that coordinates chromosome replication and cell division by a pathway different from and independent of the SOS-induced response.This publication has 1 reference indexed in Scilit:
- Coupling of DNA replication and cell division: sulB is an allele of ftsZJournal of Bacteriology, 1983