4-Hydroxy-3-nitro-2-quinolones and related compounds as inhibitors of allergic reactions
- 1 July 1975
- journal article
- Published by American Chemical Society (ACS) in Journal of Medicinal Chemistry
- Vol. 18 (7) , 726-732
- https://doi.org/10.1021/jm00241a017
Abstract
The synthesis and biological activity of a number of 4-hydroxy-3-nitro-2-quinolones are discussed and compared with their related hydroaromatic analogs. Antiallergic activity has been assessed by their ability to inhibit the homocytotropic antibody-antigen induced passive cutaneous anaphylaxis reaction in the rat.Keywords
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