Autoimmune Addison's Disease

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Abstract
THE past decades have seen a striking change in concepts of immunology, culminating in the award of the 1960 Nobel Prize for work in this field to Sir Macfarlane Burnet, of Melbourne, and P. B. Medawar, of London. Investigation by these experimenters1 , 2 has complemented the work of Witebsky and his group3 in Buffalo and of Roitt and Doniach4 in Glasgow. It has now been established that under certain circumstances, some normal autologous proteins may not be recognized as "self" by the body, and may therefore induce immunologic reactions identical with those caused by the introduction of heterologous protein. These reactions . . .