Choline Acetylase in Normal and Denervated Submaxillary Glands of Rats after Repeated Teeth Amputations

Abstract
The size of the rat's submaxillary gland and the total activity of choline acetylase in the gland were markedly and similarly increased after repeated teeth amputations. Preganglionic parasympathet‐ic denervation caused an atrophy of the gland and a pronounced decrease in enzyme activity. It did not inhibit the effects of repeated teeth amputations. Postganglionic sympathetic denervation alone caused a slight decrease in gland weight and an increase in choline acetylase activity. The effect of repeated teeth amputations was partly inhibited in sympathetically denervated glands. It was completely abolished in both parasympathetically and sympathetically denervated glands.