Phenytoin prolongs far‐field somatosensory and auditory evoked potential interpeak latencies
- 1 January 1982
- journal article
- research article
- Published by Wolters Kluwer Health in Neurology
- Vol. 32 (1) , 85
- https://doi.org/10.1212/wnl.32.1.85
Abstract
Far-field auditory and somatosensory evoked potentials were recorded in 163 epileptic patients and 31 normal controls. Analysis of variance revealed significant effects on interpeak latencies of age, sex, and phenytoin levels in three ranges: subtherapeutic, therapeutic, and toxic. Toxic levels of phenytoin may affect peripheral and central axons, slowing conduction. Therapeutic levels of phenytoin may prolong far-field interpeak latencies by acting on synapses.This publication has 0 references indexed in Scilit: