RADIATION EFFECTS ON THE PAROTID-GLAND OF MAMMALS .4. BIOCHEMICAL AND MORPHOLOGICAL-CHANGES AFTER LOCAL IRRADIATION

  • 1 January 1980
    • journal article
    • research article
    • Vol. 156  (1) , 69-72
Abstract
Rat parotids were morphologically and biochemically studied to evaluate the modifications after 2400 rad in the parotid area only. Whole-body irradiation with lower doses produced only slight effects on the gland. The enzymes peculiar to glandular function decreased significantly 3 days after irradiation, later they fluctuated on control values. Increases in alkaline phosphatase, LAP [leucine aminopeptidase] and decrease in protein content always occurred. .beta.-Glucuronidase among lysosomal enzymes increased significantly at some intervals. Morphological alterations in the glandular sections of the sacrificed animals appeared modest and consisted mostly of progressive fibrosis.

This publication has 0 references indexed in Scilit: