Pentolinium in the Management of Autonomic Hyperreflexia

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Abstract
Patients with high spinal cord injuries frequently will develop a syndrome of autonomic hyperreflexia when stimulated by urological instrumentation. Severe sustained hypertension is the most hazardous component encountered during this reaction. A series of patients exhibiting this condition was studied, who were managed safely and successfully by the use of the ganglionic blocking agent, pentolinium.