Precursor mRNA from Erythroid-Enriched Bone-Marrow Cells of the Rabbit. Electron Microscope Investigation of Precursor mRNA Molecules, Molecular Weight about 1.7 x 107, Containing mRNA-Like Structures at One End

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Abstract
Precursor mRNA (pre-mRNA) molecules, sedimenting at greater than 45 S, from erythroid-enriched bone marrow cells of the rabbit and hemoglobin mRNA molecules from rabbit reticulocytes were investigated by electron microscopy. Four of 98 measured pre-mRNA molecules had a length between 15 and 17.1 mum. In some of the pre-mRNA molecules a characteristic condensed structure was observed at one end, strikingly resembling the structure of the mRNA molecules.