The effects of X-rays upon mitotic cell division in tissue culturesin Vitro

Abstract
The earliest recognizable effect of x-radiation on growing cells is the temporary inhibition of the onset of mitosis in the majority of cells which are about to divide. Cells actually in mitosis are unaffected. It thus appears that vegetative cells pass through a phase immediately prior to visible prophase during which the physiological processes are easily disturbed by x-rays. With a dose greater than 30e, mitosis will begin but will be abnormal. There was no evidence of any stimulating effect on cell division.

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