A CASE OF ARSENIC PERIPHERAL NEURITIS TREATED WITH SYNTHETIC VITAMIN Be AND ALPHA-TOCOPHEROL

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Abstract
This report1concerns observations on the effect of parenterally administered vitamin B6and alpha-tocopherol in a case of arsenic peripheral neuritis which had been treated unsuccessfully with thiamine hydrochloride. S. A., a salesman aged 35 who had been in good health, was admitted to the Cincinnati General Hospital on Nov. 28, 1939, with acute arsenic poisoning following the ingestion of a teaspoonful of "rat embalmer" (arsenic trioxide). Vomiting and diarrhea subsided after a week of hospitalization and general supportive therapy. At the end of the second week he complained of numbness and tingling sensations in his hands and right foot. (His left leg had been amputated traumatically in 1930). Stabbing and cramping pains appeared in his hands and the calf of his right leg and became so severe that he was unable to rest. His hands became so weak that he could not pick up small objects. The

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