Abstract
Some minor changes in the original procedure are introduced. The use of Folin-Wu filtrates for the titration of icteric sera is recommended. Thiosulfate as present in blood and urine during clearance studies interferes with the mercurimetric titration. The open Carius method of Van Slyke and Sendroy is recommended when chloride is to be detd. in blood and urine containing thiosulfate. The optimal pH for chloride titration will introduce a slight error when bromide is present.