Dehydrative Sialylation with C2-Hemiketal Sialyl Donors
- 14 June 2003
- journal article
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 5 (14) , 2539-2541
- https://doi.org/10.1021/ol034815z
Abstract
A new method for sialylation involving the dehydrative coupling of sialyl donors with the reagent combination of (p-nitrophenyl)(phenyl) sulfoxide and triflic anhydride is reported. This process establishes sialyl C2-hemiketals as viable sialyl donors for complex carbohydrate synthesis.Keywords
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