Stereoselective dysmorphogenicity of the enantiomers of the valproic acid analogue 2-N-propyl-4-pentynoic acid (4-yn-VPA): Cross-species evaluation in whole embryo culture
- 1 May 1997
- journal article
- research article
- Published by Wiley in Teratology
- Vol. 55 (5) , 314-318
- https://doi.org/10.1002/(sici)1096-9926(199705)55:5<314::aid-tera3>3.0.co;2-z
Abstract
No abstract availableKeywords
This publication has 14 references indexed in Scilit:
- Validation of an in Vitro Teratology System Using Chiral Substances: Stereoselective Teratogenicity of 4-yn-Valproic Acid in Cultured Mouse EmbryosToxicology and Applied Pharmacology, 1995
- Developmental toxicity of methanol in whole embryo culture: a comparative study with mouse and rat embryosToxicology, 1993
- Effects of the antiepileptic drug valproate on metabolism and function of inhibitory and excitatory amino acids in the brainNeurochemical Research, 1993
- Valproic acid‐induced spina bifida: A mouse modelTeratology, 1992
- The Enantiomers of the Valproic Acid Analogue 2-n-Propyl-4-pentynoic Acid (4-yn-VPA): Asymmetric Synthesis and Highly Stereoselective Teratogenicity in MicePharmaceutical Research, 1992
- Effects of valproic acid, some of its metabolites and analogues on prenatal development of rats in vitro and comparison with effects in vivoArchives of Toxicology, 1990
- Asymmetric synthesis and enantioselective teratogenicity of 2-n-propyl-4-pentenoic acid (4-en-VPA), an active metabolite of the anticonvulsant drug, valproic acidToxicology Letters, 1989
- Evaluation of valproic acid (VPA) developmental toxicity and pharmacokinetics in Sprague-Dawley ratsFundamental and Applied Toxicology, 1988
- Fetal growth, major malformations, and minor anomalies in infants born to women receiving valproic acidThe Journal of Pediatrics, 1986
- Quantitation of rat embryonic development in vitro: A morphological scoring systemTeratology, 1981