Hehoglobin Brest [β127(H5)Gln→LYS] a new Unstable Human Hemoglobin Variant Located at the α1β1 Interface with Specific Electrophoretic Behavior
- 1 January 1988
- journal article
- research article
- Published by Taylor & Francis in Hemoglobin
- Vol. 12 (2) , 179-188
- https://doi.org/10.3109/03630268808998024
Abstract
Hb Brest [.beta.127(H5)Gln .fwdarw. Lys] is a new unstable variant located at the .alpha.1.beta.1 interface at the same position as Hb Complutense [.beta.127(H5)Gln .fwdarw. Glu]. In each of these, the substitution produces a distinct alteration in charge, yet both variants move with Hb A in conventional electrophoresis. This peculiar electrophoretical behavior may be due to the molecular position of the modified residue, which is deeply buried inside the tetramer.This publication has 13 references indexed in Scilit:
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