GROWTH OF EYE AND ORBIT IN CHICK-EMBRYO .9. DEVELOPMENT OF EYE AND SKULL COMPONENTS IN 3-TO-9-DAY-OLD EMBRYOS WITH ARTIFICIALLY INDUCED BILATERAL MICROPHTHALMIA

  • 1 January 1976
    • journal article
    • research article
    • Vol. 14  (2) , 139-164
Abstract
On the 3rd day of incubation, the lenses were removed from both eye primordia of chick embryos later sacrificed at the ages of 5, 7 and 9 days and fixed in a 70% alcohol solution. Analysis was made of the consequences of the absence of normal large eyes upon the structure and growth of the skull. Immediatley after the operation no changes in the head mesenchyme were observed, but during the next days, as growth continued, abnormal proportions and dimensions developed in the anterior part of the skull. Generally, this part of the skull was depressed and shorter than normal; cartilages around the eye had a different position and smaller dimensions. Perfect symmetry was only rarely maintained. A buckled interorbital septum and the deviation of the upper beak suggested a labile balance in the skull.