Microwave-accelerated Suzuki cross-coupling reaction in polyethylene glycol (PEG)
- 29 May 2001
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Green Chemistry
- Vol. 3 (3) , 146-148
- https://doi.org/10.1039/b102337n
Abstract
Polyethylene glycol (PEG) is found to be an inexpensive and non-toxic reaction medium for the microwave-assisted Suzuki cross-coupling of arylboronic acids with aryl halides. This environmentally friendly microwave protocol offers ease of operation and enables recyclability of catalyst and synthesis of a variety of substituted biaryls employing palladium chloride as catalyst and potassium fluoride as the base.Keywords
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