Influence of the Genotype of Mice on the Effect of Interferon on Phagocytic Activity of Macrophages
- 1 May 1983
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 173 (1) , 27-31
- https://doi.org/10.3181/00379727-173-41604
Abstract
The influence of genotype on interferon effect on phagocytic activity of unstimulated mouse peritoneal macrophages (MPM) was studied in in vitro experiments. Treatment of MPM from BALB/c and ICR mice with mouse fibroblast interferon (MuIFN-β) enhanced the ingestion of non-opsonized Escherichia coli. This effect was dose-dependent and neutralized by anti-interferon globulin. MPM from C57B1/6 mice were not stimulated by the same treatment. Treatment of MPM with pH 2-sensitive immune interferon (MuIFN-γ) depressed the ingestion independently on the genotype of mice.This publication has 6 references indexed in Scilit:
- EFFECT OF HUMAN LEUKOCYTE INTERFERON ON PHAGOCYTIC ACTIVITY OF POLYMORPHONUCLEAR LEUKOCYTESActa Pathologica Microbiologica Scandinavica Series B: Microbiology, 1982
- EFFECT OF INTERFERON PREPARATIONS ON THE UPTAKE OF NON‐OPSONIZED ESCHERICHIA COLI BY MOUSE PERITONEAL MACROPHAGESActa Pathologica Microbiologica Scandinavica Section B Microbiology, 1981
- Antiproliferative Action of Interferon on Murine Bone-Marrow Derived Macrophages is Influenced by the Genotype of the Marrow-Donor*Journal of Interferon Research, 1981
- Effect of Gamma Interferon Preparations onin vitroPhagocytosis and Degradation ofEscherichia coliby Mouse Peritoneal MacrophagesJournal of Interferon Research, 1981
- Genes coding for sensitivity to interferon (IfRec) and soluble superoxide dismutase (SOD-1) are linked in mouse and man and map to mouse chromosome 16.Proceedings of the National Academy of Sciences, 1980
- UPTAKE OF NON-OPSONIZED ESCHERICHIA-COLI BY UNSTIMULATED MOUSE PERITONEAL-MACROPHAGES1979