Abstract
I have been impressed, during a period of many years, with the variation of the postmortem picture at the base and on the cortex after meningeal death. All physicians have noted many times the well organized exudate at the base of the brain and the thin, flocculent, purulent exudate that covers the pia in the sulci and on the surface of the brain. It was certainly twenty-five years ago that I was first struck with this observation, but it has only been within recent years that I have been impressed with the significance of it. This well organized exudate represents the point of entrance of the infection and nature's effort to confine it. It is the sign post pointing to the field which is to be considered here. The floor of this involved area is the roof of the posterior ethmoidal cells, the sphenoid sinuses and the basilar process of

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