Influenza Anti-Neuraminidase: The Second Best Antibody
- 22 June 1972
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 286 (25) , 1360-1361
- https://doi.org/10.1056/nejm197206222862511
Abstract
The influenza virus is composed of four major structural proteins: the nucleoprotein and the membrane protein, which are located internally, and the hemagglutinin and the neuraminidase, which are located externally.1 The infected host may respond immunologically by producing antibodies to all four proteins. Since antibodies to the internal proteins appear to offer no protective advantage, our attention is directed largely toward the two external proteins.The hemagglutinin and the neuraminidase are morphologically and antigenically distinct structures on the surface of the virus. Both may independently undergo antigenic mutation. These facts have led to the institution of a completely new system . . .Keywords
This publication has 4 references indexed in Scilit:
- Influenza: The VaccinesHospital Practice, 1971
- Studies with Avian Influenza A Viruses: Cross Protection Experiments in ChickensJournal of General Virology, 1971
- Protective Effects of Specific Immunity to Viral Neuraminidase on Influenza Virus Infection of MiceJournal of Virology, 1968