Structure of simian virus 40 at 3.8-Å resolution
- 28 November 1991
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 354 (6351) , 278-284
- https://doi.org/10.1038/354278a0
Abstract
The crystallographically determined structure of simian virus 40 shows that the 72 pentamers of viral protein VP1, which form the outer shell, have identical conformations except for the C-terminal arms of their subunits. Five arms emerge from each pentamer and insert into neighbouring pentamers. This tying together of standard building blocks allows for the required variability in packing geometry without sacrificing specificity.Keywords
This publication has 46 references indexed in Scilit:
- Analysis of the structure of a common cold virus, human rhinovirus 14, refined at a resolution of 3.0 ÅJournal of Molecular Biology, 1990
- Site-directed mutation affecting polyomavirus capsid self-assembly in vitroNature, 1987
- Structure and assembly of turnip crinkle virusJournal of Molecular Biology, 1986
- Structure of tomato bushy stunt virus IVJournal of Molecular Biology, 1983
- Divalent cation sites in tomato bushy stunt virusJournal of Molecular Biology, 1983
- DNA Tumor VirusesFEBS Letters, 1982
- Resolution of simian virus 40 proteins in whole cell extracts by two-dimensional electrophoresis: Heterogeneity of the major capsid proteinCell, 1976
- The structure of viruses of the papilloma-polyoma typeJournal of Molecular Biology, 1969
- Structure of viruses of the papilloma-polyoma typeJournal of Molecular Biology, 1965
- Physical Principles in the Construction of Regular VirusesCold Spring Harbor Symposia on Quantitative Biology, 1962