Chronic subclinical inflammation in phakic eyes with intraocular lenses to correct myopia

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Abstract
An Carlos University Hospital, Madrid, Spain. Methods: Thirty eyes with a Worst-Fechner IOL and 30 eyes with a Baikoff ZB5M IOL were evaluated using the flare mode of a laser flare-cell meter. Patients in each group were divided into three subgroups of 10 eyes each according to when the postoperative flare measurements were done: 12 months, 18 months, and 24 months. Thirteen phakic eyes with myopia greater than −6.00 diopters were used as controls. Results: Postoperative flare in the Worst-Fechner group was 27.05 ± 19 photons per millisecond (photons/ms) (mean ± SD) at 12 months, 18.09 ± 17.38 photons/ms at 18 months, and 31.03 ± 28.8 photons/ms at 24 months. Postoperative flare in the Baikoff group was 21.1 ± 5.9 photons/ms at 12 months, 16.13 ± 8.3 photons/ms at 18 months, and 21.05 ± 23.5 photons/ms at 24 months. Flare in the control group was 4.24 ± 2.8 photons/ms. Postoperative flare values were significantly higher in both IOL groups than in the control group at all follow-ups (Mann-Whitney test, P < .05). Postoperative flare values in the Worst-Fechner group were higher than in the Baikoff group at 12, 18, and 24 months, although the difference was not significant (Mann-Whitney test, P > .05). Conclusions: Our study shows chronic subdinical inflammation between 1 and 2 years after implantation of both IOL types. cReprint requests to Juan J. Pérez-Santonja, MD, Sorolla 32-3, 03420-Castalla, Alicante, Spain. © Williams & Wilkins 1996. All Rights Reserved....