Quantitative approach to the study of regional lung function in children using krypton 81m

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Abstract
81mKr has many advantages for pediatric lung imaging, although the proper interpretation of ventilation and perfusion lung scans requires the quantitative analysis of the steady state images and clearance curves. The theory and practice are described and illustrated in 11 pediatric cases aged from 18 days to 14 yr. It was possible to calculate the regional distributions of ventilation and perfusion and the normalized ventilation-perfusion (.ovrhdot.V.ovrhdot.Q) ratios. Of greater functional significance was the detection of differences between the clearance rates of inhaled and infused 81mKr within single regions, since such differences reflected the dispersion of .ovrhdot.V/.ovrhdot.Q ratios among lung units within individual regions.

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