Sensitivity to Coccidioidin Among Boys in an Eastern Preparatory School

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Abstract
Of 680 students at an eastern preparatory school for boys, 17, or 2.5%, reacted to the intra-cutaneous injection of a 1:100 dilution of coccidioidin prepared on synthetic medium. While none of the 17 reactors had been previously diagnosed as having had coccidioidomy-cosis, 9 of them had spent some time in 1 or more of the southwestern States, while 8 had never been west of the Mississippi River. Of the 17 who reacted to coccidioidin, 12 failed to react to the intracutaneous injection of old tuberculin, and 5 of these 12 showed calcified nodules on roentgenological examination.