Clonidine
- 1 October 1995
- journal article
- pain therapy
- Published by Wolters Kluwer Health in Current Opinion In Anesthesiology
- Vol. 8 (5) , 455-460
- https://doi.org/10.1097/00001503-199510000-00017
Abstract
This review of the current uses of clonidine in anesthesiology and pain management emphasizes its spinal application either singly or together with other agents such as local anesthetics or opioids. New preclinical information on interactions between noradrenergic, cholinergic and opioid systems, along with promising clinical data offer a rationale for novel combination therapies of clonidine and other agents to achieve potent analgesia with minimal side effects.Keywords
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