An Open Comparison of Amiodarone* with Diltiazem and Glyceryl Trinitrate in Patients with Stable Exertional Angina

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Abstract
The haemodynamic and electrocardiographic effects of amiodarone, diltiazem, and glyceryl trinitrate (nitroglycerin) were compared in an open study of 18 patients with stable exertional angina using a graded treadmill exercise test, Amiodarone and diltiazem exerted similar antianginal effectiveness as assessed by increases in exercise performance and duration of exercise, as well as decreases in ST-segment depression, The antianginal efficacy of glyceryl trinitrate was somewhat lower than that of the other 2 agents, All the drugs were well tolerated