Specific CT findings in Krabbe disease

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Abstract
Specific computed tomography (CT) findings in four patients with biochemically proven Krabbe disease included symmetric increased attenuation in the cerebellum, brainstem, thalami, caudate nuclei, and corona radiata before and in conjunction with decreased attenuation of white matter followed by atrophy at a later stage. Familiarity with the CT findings in the acute phase of Krabbe disease may assist clinicians in limiting the differential diagnosis and requesting appropriate laboratory tests.

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