THE ACTION OF ATROPINE AND ADRENALINE ON GASTRIC TONUS AND HYPERMOTILITY INDUCED BY INSULIN HYPOGLYCEMIA

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Abstract
Hypermotility Eroduced in the stomach of a fasting gastric-fistula dog y the subcutaneous injection of insulin was inhibited, and the increased tonus was lowered by giving atropine in physiologic dosage. This effect was not accompanied by any increase in the blood sugar. Adrenaline hydro-chloride, injected intravenously during gastric hypermotility accompanying hypoglycemia, caused a lowering of tonus and inhibition of the active stomach contractions. This effect was not due to increase in blood sugar. The experimental results suggest the possibility that the hypertonicity of the starving infant may be due to an increased central nervous irritability caused to some extent by an existing hypoglycemia.

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