A discordance between cytochrome P450 2D6 genotype and phenotype in patients undergoing methadone maintenance treatment

This publication has 38 references indexed in Scilit:

• Regioselective hydroxylation of debrisoquine by cytochrome P4502D6: implications for active site modelling
  Xenobiotica, 2000
• Population pharmacokinetics of methadone in opiate users: characterization of time‐dependent changes
  British Journal of Clinical Pharmacology, 1999
• Polymorphism of the cytochrome P450 CYP2D6 gene in a European population: characterization of 48 mutations and 53 alleles, their frequencies and evolution
  Pharmacogenetics, 1997
• Geographical/Interracial Differences in Polymorphic Drug Oxidation
  Clinical Pharmacokinetics, 1995
• “It's the genes, stupid” Molecular bases and clinical consequences of genetic cytochrome P450 2D6 polymorphism
  Life Sciences, 1995
• Pharmacogenetic Phenotyping and Genotyping
  Clinical Pharmacokinetics, 1994
• Inhibition of human cytochrome P450 2D6 (CYP2D6) by methadone.
  British Journal of Clinical Pharmacology, 1993
• The Human Hepatic Cytochromes P450 Involved in Drug Metabolism
  Critical Reviews in Toxicology, 1992
• The genetic polymorphism of debrisoquine/sparteine metabolism — Clinical aspects
  Pharmacology & Therapeutics, 1990
• Identification of the primary gene defect at the cytochrome P450 CYP2D locus
  Nature, 1990