Developing an AIDS Vaccine: Need, Uncertainty, Hope
- 25 June 2004
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 304 (5679) , 1913-1914
- https://doi.org/10.1126/science.1100368
Abstract
It is more than 20 years since the identification of HIV, the virus that causes AIDS. In their Perspective, Emini and Koff discuss how far we have come in understanding the interaction of HIV with the host immune system, and what we must learn to develop an effective vaccine that will halt the spread of AIDS.Keywords
This publication has 11 references indexed in Scilit:
- Brief but Efficient: Acute HIV Infection and the Sexual Transmission of HIVThe Journal of Infectious Diseases, 2004
- Rapid Clearance of Virus after Acute HIV‐1 Infection: Correlates of Risk of AIDSThe Journal of Infectious Diseases, 2004
- HIV vaccine design and the neutralizing antibody problemNature Immunology, 2004
- Prospects for an AIDS vaccineNature Medicine, 2004
- Reversion of CTL escape–variant immunodeficiency viruses in vivoNature Medicine, 2004
- Immunopathogenesis and immunotherapy in AIDS virus infectionsNature Medicine, 2003
- CD8 T Cells Remember with a Little HelpScience, 2003
- Broadly Neutralizing Antibodies Targeted to the Membrane-Proximal External Region of Human Immunodeficiency Virus Type 1 Glycoprotein gp41Journal of Virology, 2001
- Design of potent inhibitors of HIV-1 entry from the gp41 N-peptide regionProceedings of the National Academy of Sciences, 2001
- The HIV-1 Envelope Glycoproteins: Fusogens, Antigens, and ImmunogensScience, 1998