Rare Purine Nucleosides: Congeners of the Antibiotic, Nebularine
- 1 January 1988
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 1988 (11) , 848-850
- https://doi.org/10.1055/s-1988-27727
Abstract
Novel functionalized analogues of the biologically active nucleoside, nebularine, have been synthesized. The key step of the syntheses involved palladium-catalyzed cross-coupling reactions between 2-iodonebularine and organostannanes. This synthetic approach has considerable potential generality, and the only limitation appears to be the availability of the appropriate organostannane coupling reagent.Keywords
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