Mapping cerebral blood flow by xenon-enhanced computed tomography: clinical experience.

Abstract
Local cerebral blood flow was measured and mapped using Xe-enhanced X-ray transmission computed tomography. Studies involving 4-6 min of Xe-O2 inhalation can be performed routinely in awake and anesthetized patients with acceptable patient tolerance and compliance. Several case studies of patients with acute and chronic ischemic injuries and other cerebral abnormalities are presented to illustrate characterization of flow pattern in normal and abnormal tissue, as well as the relevance of this flow information to clinical patient management.