Effects of Nitrous Oxide—Curare, Ether and Cyclopro pane on Postoperative Respiratory Adequacy

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Abstract
Postoperative ventilatory status was studied in 3 groups of patients totaling 79: the first group anesthetized with N2O and large doses of d-tubocurare followed by complete reversal with neostigmine, a second with N2O-ether and a third with cyclopropane. Changes in arterial blood gases and inspiratory force were the criteria used. Significant differences among the groups occurred only in the first hour postoperatively: CO2 retention in cyclopropane group compared to other groups and less acidosis and higher inspiratory force measurements in female patients receiving curare, when a nerve muscle stimulator was used to define complete reversal of curarization.

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