Blood Selenium and Glutathione Peroxidase Levels and Dietary Selenium of Free-Living and Institutionalized Elderly Subjects

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Abstract
The Se status of healthy free-living and institutionalized elderly people was evaluated. For the 36 free-living elderly dietary Se intake average 94 .+-. 44 .mu.g Se/day and a positive correlation coefficient was found between dietary Se and dietary calories (r = 0.46; P < 0.05), dietary protein (r = 0.60; P < 0.01) and dietary fat (r = 0.43; P < 0.05). Diet histories from the institutionalized subjects revealed a strong correlation coefficient between Se and carbohydrate (r = 0.51; P < 0.005) and Se and calories (r = 0.44; P < 0.05). Mean erythrocyte and plasma Se levels for the free-living subjects were 0.20 .+-. 0.06 and 0.10 .+-. 0.03 .mu.g/ml, respectively, while mean erythrocyte glutathione peroxidase (GSH-Px) activity was 27.5 .+-. 5.0 U/g protein. For the free-living subjects positive correlation was found between dietary Se and erythrocyte Se levels (r = 0.38; P < 0.05), but no correlation existed between dietary Se and plasma Se (r = 0.13; P > 0.05) and RBC [red blood cell] GSH-Px (r = -0.15; P > 0.05). The dietary Se levels and blood Se and GSH-Px levels were above the levels found in populations proposed to be at risk for Se deficiency. These elderly appear to have adequate Se status.

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