Albendazole Therapy for Neurocysticercosis-Reply

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Abstract
In Reply. —The short course of treatment for neurocysticercosis with albendazole1 was based on the following observations: the adverse reactions to praziquantel or to albendazole occur only during the first days of the antiparasitic treatment2,3; these reactions have been interpreted as predictors of a favorable therapeutic outcome, since they are secondary to the destruction of the parasites.2-4 In an unpublished study that was carried out in our department, prior to carrying out the shortened course of treatment,1 we found that, among the 20 patients with neurocysticercosis who were administered albendazole for 30 days,2 the adverse reactions occurred between the second and third days after treatment was initiated in 65% of the cases (13/20), and remission in these patients occurred at the end of the first week with the aid of symptomatic drugs, as other studies have reported2,5; in this unpublished study with 20

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