Forced-flow bioreactor for sucrose inversion using ceramic membrane activated by silanization
- 19 February 1989
- journal article
- research article
- Published by Wiley in Biotechnology & Bioengineering
- Vol. 33 (7) , 856-861
- https://doi.org/10.1002/bit.260330709
Abstract
A forced‐flow enzyme membrane reactor system for sucrose inversion was investigated using three ceramic membranes having different pore sizes. Invertase was immobilized chemically to the inner surface of a ceramic membrane activated by a silane—glutaraldehyde technique. With the cross‐flow filtration of sucrose solution, the reaction rate was a function of the permeate flux, easily controlled by pressure. Using 0.5 μm support pore size of membrane, the volumetric productivity obtained was 10 times higher than that in a reported immobilized enzyme column reactor, with a short residence time of 5 s and 100% conversion of the sucrose inversion.This publication has 15 references indexed in Scilit:
- New enzyme reactor with forced flow of the substrate through an enzyme immobilized ceramic membrane.Agricultural and Biological Chemistry, 1988
- Fundamental studies of glucose oxidase immobilization on controlled pore glassBiotechnology & Bioengineering, 1985
- High-temperature immobilized-cell ultrafiltration reactorsJournal of Membrane Science, 1982
- Some observations on the similarity of batch and plug‐flow systems as applied to enzyme reactors*Biotechnology & Bioengineering, 1981
- Characteristics of immobilized invertaseBiotechnology & Bioengineering, 1980
- A method for preparing bead shaped immobilized enzyme.Agricultural and Biological Chemistry, 1976
- Continuous hydrolysis of sucrose by invertase adsorbed in a tubular reactorBiotechnology & Bioengineering, 1975
- Enzyme-coupled ultrafiltration membranesBiotechnology & Bioengineering, 1975
- Invertase covalently coupled to porous glass: Preparation and characterizationBiotechnology & Bioengineering, 1972
- Diffusion in the sucrose + water systemTransactions of the Faraday Society, 1964