Cloning and Biochemical Characterization of a Class A β-Lactamase from Prevotella intermedia
- 1 August 2001
- journal article
- research article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 45 (8) , 2386-9
- https://doi.org/10.1128/aac.45.8.2386-2389.2001
Abstract
The gene encoding a β-lactamase of Prevotella intermedia was cloned and sequenced. This gene, called cfxA2 , shared 98% identity with cfxA , the structural gene of a β-lactamase previously described in Bacteroides vulgatus . The deduced protein sequence had a K272E substitution. CfxA2 had the characteristics of class A, group 2e β-lactamases.Keywords
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