Enzymatic Acylation and Ring-Closing Olefin Metathesis: A Convenient Strategy for the Lactone Moiety of Compactin and Mevinolin
- 1 July 2000
- journal article
- research article
- Published by American Chemical Society (ACS) in The Journal of Organic Chemistry
- Vol. 65 (15) , 4779-4781
- https://doi.org/10.1021/jo000528m
Abstract
No abstract availableThis publication has 20 references indexed in Scilit:
- Nonpeptidal P2 Ligands for HIV Protease Inhibitors: Structure-Based Design, Synthesis, and Biological EvaluationJournal of Medicinal Chemistry, 1996
- Synthesis and biological activity of new HMG-CoA reductase inhibitors. 3. Lactones of 6-phenoxy-3,5-dihydroxyhexanoic acidsJournal of Medicinal Chemistry, 1991
- Conversion of D-Glucose into the .BETA.-Hydroxy-.DELTA.-lactone Moiety of Mevinic Acids and Congeners via D-Idose as a Key Chiral Intermediate.CHEMICAL & PHARMACEUTICAL BULLETIN, 1991
- New Aspects of Stereoselective Synthesis of 1,3-PolyolsSynthesis, 1990
- A Facile Chiral Synthesis of the Lactone Moiety of Compactin and Mevinolin from (R)-O-BenzylglycidolSynthesis, 1989
- Organoselenium-mediated Reduction of α, β-Epoxy Esters to β-Hydroxy EstersChemistry Letters, 1988
- Organoselenium-mediated reduction of α,β-epoxy ketones to β-hydroxy ketones: A new access to inter- and intramolecular aldolsTetrahedron Letters, 1987
- EFFECTS OF SYNVINOLIN (MK-733) ON PLASMA LIPIDS IN FAMILIAL HYPERCHOLESTEROLAEMIAThe Lancet, 1986
- 3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors. I. Structural modification of 5-substituted 3,5-dihydroxypentanoic acids and their lactone derivativesJournal of Medicinal Chemistry, 1985
- .alpha.-Methoxy-.alpha.-trifluoromethylphenylacetic acid, a versatile reagent for the determination of enantiomeric composition of alcohols and aminesThe Journal of Organic Chemistry, 1969