The Practical Management of Depression

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Abstract
MORE HUMAN SUFFERING has resulted from depression than from any other single disease. Despite their relatively recent introduction into medical practice, antidepressants are used in the treatment of over 4 million patients a year in the United States. Unfortunately our inability to detect certain types of depression or to get all obvious cases to come for therapy contribute to 20,000knownsuicides a year in the US, and at least twice that number who go undetected. Two million persons in this country are estimated to have made at least one suicidal attempt.2Multiple millions more of mildly depressed patients never seek help because they actually fail to realize that they are ill. Lest it be felt this is a peculiarly American phenomenon, the evidence is clear that depression is world-wide in distribution and probably in incidence. Earlier theories that it was nonexistent or extremely low in certain parts of

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