VASOCONSTRICTION AS A PRECIPITATING FACTOR IN TRAUMATIC SHOCK IN THE DOG

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Abstract
Two types of trauma[long dash]digital manipulation of the upper abdomen and contusion of the muscles of the hind legs[long dash]gave similar changes in pressure and cardiac output. Closely related to the onset and intensity of the trauma was a marked rise in vasomotor resistance of the body. The traumatized leg itself showed early vasodilation. These changes outlasted the trauma period. The handicapping of the reflex vasoconstriction by a small dose of Dibenamine increased the survival rate after leg trauma from zero in the controls to 89%. It is concluded that the vasoconstriction renders the animal more sensitive to blood volume reduction, so that the local fluid loss into the traumatized areas constitutes a lethal hemorrhage.