THE INTERCONVERSION OF ESTRONE AND ESTRADIOL-17βBY RAT LIVER SLICES1,2,3
- 1 March 1953
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 52 (3) , 277-286
- https://doi.org/10.1210/endo-52-3-277
Abstract
Counter-current distr. and photofluorometry have been applied to the separation, characterization and quantitative estimation of estrone and estradiol after incubation with rat liver slices, The interconversion of estrone and estradiol occurs under both aerobic and anaerobic conditions. Ethanol has a slight inhibitory effect on the oxidative breakdown of estrone and estradiol. The extent of conversion of estradiol to estrone by normal and cir-rhotic rat livers and hepatoma nodules depends on the hormone concn.Keywords
This publication has 1 reference indexed in Scilit:
- Über das Schicksal des Follikelhormons (Follikulin) im Organismus1Skandinavisches Archiv Für Physiologie, 1934