Quantitative Analysis of Trace Chromium in Blood Samples. Combination of the Advanced Oxidation Process with Catalytic Adsorptive Stripping Voltammetry
- 23 September 2006
- journal article
- research article
- Published by American Chemical Society (ACS) in Analytical Chemistry
- Vol. 78 (21) , 7582-7587
- https://doi.org/10.1021/ac060707p
Abstract
A new method for pretreating blood samples for trace Cr analysis is described. The advanced oxidation process (AOP with H2O2 and 5.5-W UV irradiation for 60 min) is used to remove biological/organic species for subsequent analysis. Prior to the AOP pretreatment, acid (HNO3) is used at pH 3.0 to inhibit the enzyme catalase in the blood samples. Catalytic adsorptive stripping voltammetry at a bismuth film electrode gives a Cr concentration of 6.0 ± 0.3 ppb in the blood samples. This concentration was confirmed by dry-ashing the blood samples and subsequent analysis by atomic absorption spectroscopy. This current method may be used to monitor chromium, a trace metal in humans, and the efficacy and safety of chromium supplements as adjuvant therapy for diabetes.Keywords
This publication has 45 references indexed in Scilit:
- Electrochemical deposition of sol–gel films for enhanced chromium(VI) determination in aqueous solutionsAnalytica Chimica Acta, 2006
- Catalytic adsorptive stripping determination of trace chromium (VI) at the bismuth film electrodeTalanta, 2004
- Characterization of Chromodulin by X-ray Absorption and Electron Paramagnetic Resonance Spectroscopies and Magnetic Susceptibility MeasurementsJournal of the American Chemical Society, 2002
- Determination of Cr(III) and Cr(VI) species in natural waters by catalytic cathodic stripping voltammetryAnalytica Chimica Acta, 2001
- Influence of different types of effectors on the kinetic parameters of suicide inactivation of catalase by hydrogen peroxideBiochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1999
- The effect of freshwater UV-irradiation prior to resin preconcentration of trace metalsAnalytica Chimica Acta, 1999
- Analytical problems in the determination of platinum-group metals in urine by quadrupole and magnetic sector field inductively coupled plasma mass spectrometryPublished by Elsevier ,1998
- UV-photooxidation as pretreatment step in inorganic analysis of environmental samplesAnalytica Chimica Acta, 1996
- The inter-relationship between insulin and chromium in hyperinsulinaemic euglycaemic clamps in healthy volunteersJournal of Endocrinology, 1993
- Use of Overoxidised Polypyrrole as a Chromium(VI) SensorAnalytical Letters, 1992