Asymmetric Synthesis of Quaternary α-Amino Phosphonates Using Sulfinimines
- 1 May 2001
- journal article
- research article
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 3 (11) , 1757-1760
- https://doi.org/10.1021/ol015945f
Abstract
The addition of lithium diethylphosphonate to enantiopure ketosulfinimines is highly diastereoselective (>95%), affording the first examples of quaternary α-alkyl α-amino (arylmethyl)phosphonates.Keywords
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