A Convenient Method for the Preparation of Enantiomerically Pure 2-SubstitutedN-Tosylaziridines
- 1 January 1992
- journal article
- letter
- Published by Georg Thieme Verlag KG in Synlett
- Vol. 1992 (01) , 41-44
- https://doi.org/10.1055/s-1992-21259
Abstract
A three-step procedure for the synthesis of enantiomerically pure 2-substituted N-tosylaziridines 4 is described. The method involves N-tosylation of (S)-2-amino acids 1, followed by reduction to give N-tosyl-2-amino alcohols 3 and O-tosylation with in situ aziridine ring closure.Keywords
This publication has 0 references indexed in Scilit: