Fractionation of Radioactive B12-Complex In Kidney Homogenates.
- 1 July 1957
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 95 (3) , 517-520
- https://doi.org/10.3181/00379727-95-23273
Abstract
The amount of radioactive B12 bound by substances in kidneys of rats pre-injected with this radiovitamin was found to be approximately one-half to two-thirds of the total radioactivity by 4 independent procedures. The amounts of radioactivity in the 3 fractions obtained by differential centrifugation were also determined with only a small portion in the mitochondria. Relative percentages of the radioactivity in these 3 components remained essentially unchanged as a result of pre-injection of unlabeled B12.Keywords
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